Scientific Evidence
As Spimed-AI is based on medical research and development,
we publish our studies in specialized scientific journals.
Our latest papers
June 22th 2024
Freely available with unlimited access
March 10th 2024
B. Mehier, K. Mahmoudi, A. Veugeois, A. Masri, N. Amabile, C. Del Giudice, JF. Paul
February 16th 2024
JM. Brendel, J Walterspiel, F Hagen, J Kübler, JF Paul, K Nikolaou,
M Gawaz, S Greulich, P Krumm, M Winkelmann
September 7th 2023
C. Glessgen, M. Boulougouri, JP. Vallée, S. Noble, A. Platon, PA. Poletti, JF. Deux, JF. Paul
June 6th 2022
Evaluation of a deep learning model on coronary CT angiography for automatic stenosis detection.
JF. Paul, A. Rohnean, H. Giroussens, T. Pressat-Laffouilhere, T. Wong,
Clinical Cases
Case 1 : AI-Assisted Automatic Extraction of curved MPR coronary CT images
Patient: Female
Age: 42
Background:
Underwent coronary CT angiography (CCTA) for chest discomfort
Automatic extraction of the 3 main coronary arteries was performed by a new research segmentation tool from CorEx, providing automated CAD-RADS classification and FFR prediction as well.
A subocclusive coronary stenosis from a non calcified plaque was detected on mid RCA confirmed by invasive coronary angiography. Patient was successfully treated by a stent (Dr Patrick Dupouy)
This case illustrates that CorEx software may help detecting automatically obstructive lesions, without needs of any human intervention. AI may then help to democratize the usage of coronary CTA.
Case 2 : Spontaneous LAD dissection revealed by coronary CT angiography
Patient: Female
Age: 46
Background:
No cardiovascular risk factors. Subject underwent coronary CT angiography (CCTA) for acute coronary syndrome
and had blood elevation of troponins: Patient underwent coronary CT angiography (CCTA).
AI-based CorEx software with automated segmentation revealed long LAD stenosis.
Surrounded with diffuse mural thickening, without any calcification, compatible with a coronary wall hematoma. Invasive coronary angiography was subsequently performed confirming moderate stenosis of the proximal LAD, with intra-mural LAD hematoma confirmed by Optical Coherence Tomography (Dr Khalil Mammoudi).
Patient was treated medically with Aspirin and beta-blockers, leading to total recovery and complete regression
of the stenosis on the CCTA performed 3 months later
Spontaneous coronary dissection is a rare cause of acute coronary syndrome, often affecting women between
30 and 60 years.
CCTA may be useful for diagnosis and follow-up
Case 3 : Coronary CCTA before returning to sport activity
Patient: Male
Age: 72
Background:
Wants to return to sport activity. Underwent coronary CT angiography (CCTA) Has high blood cholesterol
and mild carotid plaque.
A long very severe coronary stenosis of the right coronary artery (RCA) from a partially calcified plaque was detected on mid RCA (CorEx software, Spimed-AI).
Subocclusive lesion was confirmed by invasive coronary angiography.
The patient was successfully treated by 2 stents on RCA.
This case illustrates that asymptomatic patients over 50 years of age may benefit from CCTA before returning
to sport activity.